An Introduction to Genetic Analysis

Principles of Genetics Analysis

A two part introductory course on  Genetics

  This course leads to an introduction and to an advanced course in Genetics Analysis

This course is FREEly offered by MIT Open Courseware.

Hawaii On Line University offers this course under the Creative Commons License from MIT who states in its web site: ““The idea is simple: to publish all of our course materials online and make them widely available to everyone.” Dick K.P. Yue, Professor, MIT School of Engineering.

You are free to:Share — copy and redistribute the material in any medium or format, Adapt — remix, transform, and build upon the material. The licensor cannot revoke these freedoms as long as you follow the license terms.

We Define Details of this course here:

Course Description

“This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.” (MIT University, 2004)


MIT Instructor(s)

Prof. Chris Kaiser, Prof. Gerald Fink, Prof. Leona Samson, Dr. Michelle Mischke

MIT Course Number 7.03

As Taught In Fall 2004- Level Undergraduate

Course Meeting Times

Lectures: 3 sessions / week, 1 hour / session

Recitations: 1 session / week, 1 hour / session


There are no assigned readings for this class although we recommend the following textbook as a valuable reference.

Buy at Amazon Griffiths, Anthony J. F., Jeffrey H. Miller, David T. Suzuki, Richard C. Lewontin, and William M. Gelbart. An Introduction to Genetic Analysis

. 7th ed. New York: W. H. Freeman, 2000. ISBN: 9780716735205.

Check out the National Center for Biotechnology Information (NCBI), PubMed, Web site for an online version of this textbook.

Assignments and Exams

There are six graded problem sets for this course. Students may collaborate with classmates on the problem sets, but copying problem set solutions is not permitted. Any student that copies another problem set or allows their problem set to be copied will be assigned a 0 for that problem set.

There are three one-hour exams. The exams will be closed book, but students may bring one 8 1/2 x 11 sheet of notes to the proctored exam. In addition to the exams, there will also be a final proctored exam during exam week. The final will be comprehensive and will cover material from the entire course with an emphasis on material from lectures 31-36 not covered by an hour exam.

Contents- Part I and Part II

Part I comprises of Chapter 1-13

Part II comprises Chapter 14-26

  • Preface
  • Chapter 1. Genetics and the Organism
  • Chapter 2. Patterns of Inheritance
  • Chapter 3. Chromosomal Basis of Heredity
  • Chapter 4. Gene Interaction
  • Chapter 5. Basic Eukaryotic Chromosome Mapping
  • Chapter 6. Specialized Eukaryotic Chromosome Mapping Techniques
  • Chapter 7. Gene Transfer in Bacteria and Their Viruses
  • Chapter 8. The Structure and Replication of DNA
  • Chapter 9. Genetics of DNA Function
  • Chapter 10. Molecular Biology of Gene Function
  • Chapter 11. Regulation of Gene Transcription
  • Chapter 12. Recombinant DNA Technology
  • Chapter 13. Applications of Recombinant DNA Technology
  • Chapter 14. Genomics
  • Chapter 15. Gene Mutation
  • Chapter 16. Mechanisms of Gene Mutation
  • Chapter 17. Chromosome Mutation I: Changes in Chromosome Structure
  • Chapter 18. Chromosome Mutation II: Changes in Chromosome Number
  • Chapter 19. Mechanisms of Recombination
  • Chapter 20. Transposable Genetic Elements
  • Chapter 21. Extranuclear Genes
  • Chapter 22. Cancer as a Genetic Disease
  • Chapter 23. Developmental Genetics
  • Chapter 24. Population Genetics
  • Chapter 25. Quantitative Genetics
  • Chapter 26. Intelligent Information based Genetics (“evolution” excluded).
  • Appendices
  • Glossary



MIT University. (2004). An Introduction to Genetic Analysis. MIT Course Number 7.03. Retrieved July 11, 2018, from